| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5842877 | Life Sciences | 2011 | 8 Pages |
Abstract
These results demonstrate that U50,488H administered immediately prior to reperfusion increases Akt phosphorylation through a PI3-kinase-dependent mechanism and reduces postischemic myocardial apoptosis. Phosphorylation of eNOS with secondary NO production contribute significantly to the anti-apoptotic effect of U50,488H postconditioning.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Guang Tong, Zhongchan Sun, Xufeng Wei, Chunhu Gu, Alan David Kaye, Yuemin Wang, Juan Li, Quanyu Zhang, Haitao Guo, Shiqiang Yu, Dinghua Yi, Jianming Pei,