Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5842911 | Life Sciences | 2011 | 10 Pages |
Abstract
Knowing that the protein kinase inhibitory properties are different for each inhibitor, it seems that only a limited range of inhibitory activity is tolerated by cells. Chk1 has an essential role in determining how cancer cells respond to genotoxic treatments, therefore, inhibitors of this protein kinase are of great medical interest.
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Authors
Gilles Ferry, Aurélie Studeny, Céline Bossard, Philip M. Kubara, Denis Zeyer, Jean-Paul Renaud, Patrick Casara, Guillaume de Nanteuil, Michel Wierzbicki, Bruno Pfeiffer, Michelle Prudhomme, Stephane Leonce, Alain Pierré, Jean A. Boutin,