Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5842919 | Life Sciences | 2011 | 5 Pages |
Abstract
In conclusion, female pups treated prenatally with LPS presented an attenuated response to experimentally-induced asthma. We observed reduced immune cell migration from peripheral blood to the lungs, with no effect on the production of bone marrow cells or antibodies. It was suggested that inflammatory events such as exposure to LPS in early fetal life can attenuate allergic inflammation in the lung, which is a common symptom in asthma.
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Authors
Thiago Berti Kirsten, Beatriz Petri Soares de Oliveira, Ana Paula Ligeiro de Oliveira, Karin Kieling, Wothan Tavares de Lima, João Palermo-Neto, Maria Martha Bernardi,