Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5844368 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2015 | 24 Pages |
Abstract
The aim of the present study was to investigate the relevance of different parameters of 3,4-methylenedioxymethamphetamine (MDMA) use, including age of first use, cumulative lifetime dose and highest daily dose for predicting cognitive performance and self-reported psychopathology. Moreover, interactions between those parameters were examined. Ninety-six new MDMA users were interviewed to assess their drug use, and they completed a battery of cognitive tests concerning attention and information processing speed, episodic memory and executive functioning and self-reported psychopathology. Subjects participated again after 1Â year to provide follow-up data. Significant associations between age of first use and cumulative lifetime dose have been found for attention and information processing speed. Furthermore, the results showed a significant effect of age of first use on the recognition performance of the episodic memory. The findings of the current study provide a first estimation of the interactions between different MDMA use parameters. Future research should focus upon additional parameters of drug use and concentrate on consequent follow-up effects.
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Authors
Daniel Wagner, Sophia Adolph, Philip Koester, Benjamin Becker, Euphrosyne Gouzoulis-Mayfrank, Joerg Daumann,