| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5844394 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2015 | 7 Pages |
Abstract
Our results highlight the important role of 3â² UTR in the CHRNB2 gene in the shared molecular background of ND and depressive phenotype. Parental bonding style can be suggested as a significant environmental factor in further GxE studies of depression. The presented significant GxE interaction on smoking-related suicidal subphenotype may help establish further investigations on development of more effective and safer smoking cessation and antidepressant agents.
Keywords
FTNDCHRNB2CHRNB4CHRNA4GLMnAChRMDDcpdDNAZung self-rating depression scaleAlcMajor depressive disorderdeoxyribonucleic acidSuicidal ideationstandard deviationanalysis of varianceANOVAFagerstrom Test for Nicotine DependenceGene–environment interactionGeneralized linear modelcarbon monoxideNicotine dependenceSingle nucleotide polymorphismSNP
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Authors
Iren Csala, Luca Egervari, Peter Dome, Gabor Faludi, Balazs Dome, Judit Lazary,