| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5844480 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2014 | 6 Pages |
Abstract
Although an association between the CYP17 CC genotype and TD is indicated, our findings do not support the hypothesis that this is mediated through increased DHEA(S) levels. We believe that the relationship between this polymorphism and neuroprotective effects of steroids is more complex and cannot be elucidated without taking the posttranslational regulation of the enzyme into account.
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Authors
Svetlana A. Ivanova, Lisanne M. Geers, Asmar F.Y. Al Hadithy, Petros Pechlivanoglou, Arkadiy V. Semke, Natalia M. Vyalova, Evgeniy V. Rudikov, Olga Y. Fedorenko, Bob Wilffert, Nikolay A. Bokhan, Jacobus R.B.J. Brouwers, Anton J.M. Loonen,