Is there an association between peripheral immune markers and structural/functional neuroimaging findings?

Article ID	Journal	Published Year	Pages	File Type
5844496	Progress in Neuro-Psychopharmacology and Biological Psychiatry	2014	9 Pages	PDF

Abstract

âº Articles are reviewed about an association between immune markers and neuroimaging. âº Structural brain changes are associated with inflammation in psychiatric disorders. âº Proinflammatory cytokines seem to be implicated in functional activation anomalies. âº More studies are needed on the association between inflammation and brain changes.

Keywords

CA4 iNOS MCP-1 IL-1β IL-10 DTI VBM NMDA N-methyl-d-aspartate CA3 OFC GMV WMV ACC WMH IL-8 VCAM-1 M-CSF IL-12 SACC MPIO MIP-1 sIL-4R immunoglobulin-G pro-IL-1β GAD LPS IL-6 IL-1 IgG PFC MDD dACC glutamic acid decarboxylase SGK cornu ammonis region 3 Major depressive disorder mild cognitive impairment Schizophrenia Major depression inflammation MRI interleukin-12 Interleukin-8 Interleukin-10 interleukin-6 interleukin-1 Interleukin-1β cornu ammonis Alzheimer's disease diffusion tensor imaging Magnetic resonance imaging fMRI functional magnetic resonance imaging long-term potentiation LTP anterior Insula gray matter volume white matter volume CNS glucocorticoid-induced leucine zipper Aging central nervous system MR spectroscopy magnetic resonance spectroscopy basal ganglia prefrontal cortex orbitofrontal cortex anterior cingulate cortex dorsal anterior cingulate cortex Subgenual anterior cingulate cortex lipopolysaccharide white matter hyperintensity Gray matter white matter macrophage colony-stimulating factor Cerebrospinal fluid CSF hypothalamic–pituitary–adrenal axis voxel-based morphometry HPA fractional anisotropy Nitric oxide MCI monocyte chemo-attractant protein-1 C-reactive protein CRP cingulate cortex Gilz