| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5844566 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2014 | 6 Pages |
Abstract
It is suggested that synaptic dopamine supersensitivity in schizophrenia is an attempt at compensation for the original damage by heightening dopamine neurotransmission pathways (preparing the organism for fight or flight). The dopamine overactivity is experienced subjectively as overstimulation, which accounts for some of the clinical symptoms, with attempts at dampening down the stimulation leading to still other symptoms. Reaction and counter-reaction may explain the symptoms of schizophrenia.
Related Topics
Life Sciences
Neuroscience
Biological Psychiatry
Authors
Mary V. Seeman, Philip Seeman,