Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5844571 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 6 Pages |
Abstract
⺠SLC6A4 methylation was associated with childhood adversity in depressive patients. ⺠SLC6A4 methylation was associated with more severe depression at presentation. ⺠Associations of SLC6A4 methylation with treatment outcomes are yet to be determined. ⺠SLC6A4 methylation could be a biomarker for certain presentations of depression.
Keywords
SOFASSLC6A4LESPSSSCID5-HTTDSM-IVWHOQOL-BrefDepressionEpigeneticschildhood adversityserotonin transporterDNA methylationSocial and Occupational Functioning Assessment ScalePerceived Stress ScaleHamilton anxiety rating scaleHamilton Depression Rating ScaleHPAHAMAHAMDhypothalamo-pituitary-adrenalpolymerase chain reactionPCR
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Authors
Hee-Ju Kang, Jae-Min Kim, Robert Stewart, Seon-Young Kim, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Myung-Geun Shin, Jin-Sang Yoon,