Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5844575 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 7 Pages |
Abstract
⺠Little is known about how TRD and TSD differ in cerebellar-cerebral FC ⺠Patients with TRD are in treatment-resistant state ⺠Patients with TSD are first-episode, drug-naive, and treatment-sensitive persons ⺠FC method could detect abnormal cerebellar-cerebral FC between TRD and TSD ⺠Decreased cerebellar-DMN FC might be used to separate the two patient groups
Keywords
PCUTRDITGTCAsIPLSSRIsTSDHRSDMFGSNRIsMNIDMNMDDROIROCPFCFunctional connectivityPrecuneusMajor depressive disorderHealthy subjectsTreatment-resistant depressionanalysis of varianceANOVAframewise displacementtricyclic antidepressantsSMAGlobal signal regressiondefault mode networkInferior temporal gyrusprefrontal cortexinferior parietal lobuleTreatment resistanceHamilton Rating Scale for DepressionRegions Of InterestSelective serotonin reuptake inhibitorserotonin-norepinephrine reuptake inhibitorMontreal Neurological InstituteSMA, supplementary motor areaangular gyrusmiddle frontal gyrusreceiver operating characteristic curves
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Authors
Wenbin Guo, Feng Liu, Zhimin Xue, Keming Gao, Zhening Liu, Changqing Xiao, Huafu Chen, Jingping Zhao,