Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5844600 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 9 Pages |
Abstract
⺠Julibroside C1 showed anxiolytic-like effects in the EPM test. ⺠Julibroside C1 effects were blocked by WAY-100635, bicuculline, and flumazenil. ⺠Julibroside C1 induced alterations in 5-HT1A and GABAA receptors in the mouse brain.
Keywords
8-OH-DPATAlbizzia julibrissin5-HT1A5-hydroxytryptamineEPMNAC5-HTCPU8-hydroxy-2-(di-n-propylamino) tetralinN/OFQnociceptin/orphanin FQdistilled waterAnxiolytic effectsFRAγ-aminobutyric acidelevated plus mazebenzodiazepinefrontal cortexMotor cortexNucleus accumbensCaudate putamencingulate cortexGABAAGABA
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Authors
Yang-Hee Jung, Ri-Ra Ha, Seung-Hwan Kwon, Sa-Ik Hong, Kun-Ho Lee, Sun-Yeou Kim, Seok-Yong Lee, Choon-Gon Jang,