Antioxidants as potential therapeutics for neuropsychiatric disorders

Article ID	Journal	Published Year	Pages	File Type
5844654	Progress in Neuro-Psychopharmacology and Biological Psychiatry	2013	10 Pages	PDF

Abstract

âº Overview of oxidative stress in major neuropsychiatric disorders âº Alterations in antioxidant defense mechanisms in schizophrenia and depression âº Antioxidants hold great promise for the treatment of schizophrenia and depression.

Keywords

EPA NO−BPRS Docosahexaenoic PUFAs PANSS RNS TBARS GPX NAC GST GSH CAT BDNF TAS ONOO−ROS Antioxidant Nitroxyl anion neuropsychiatric disorders Eicosapentaenoic acid Polyunsaturated fatty acids Electroencephalography Nitrous oxide Oxidative stress DHA SOD Superoxide dismutase Brain-derived neurotrophic factor Brief Psychiatric Rating Scale positive and negative syndrome scale thiobarbituric acid reactive substances EEG Total antioxidant status Peroxynitrite Catalase reduced glutathione glutathione S transferase glutathione reductase glutathione peroxidase reactive nitrogen species Reactive oxygen species