Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5844698 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 8 Pages |
Abstract
Our data demonstrate that in patients with psychoses, met carriers of the BDNF val66met with high level of childhood abuse have more cognitive and brain abnormalities than all other groups.
Keywords
BDNF val66metPASWStructured Clinical Interview for DSM DisordersCTQproBDNFPANSSSCIDDSM-IVBDNFDNAsMRIEarly traumadeoxyribonucleic acidRNAribonucleic acidintelligence quotientStructural magnetic resonance imagingDiagnostic and Statistical Manual of Mental Disorders, fourth editionPsychosesvalemotional abusephysical abuseSexual abuseCognitionbrain derived neurotrophic factorEmotional neglectPhysical neglectMethionineWechsler Abbreviated Scale of Intelligencepositive and negative syndrome scaleMETWASIValineChildhood Trauma QuestionnaireSingle-nucleotide polymorphismSNPglucocorticoid receptor
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Authors
Monica Aas, Unn K. Haukvik, Srdjan Djurovic, Ãrjan Bergmann, Lavinia Athanasiu, Martin S. Tesli, Tone Hellvin, Nils Eiel Steen, Ingrid Agartz, Steinar Lorentzen, Kjetil Sundet, Ole A. Andreassen, Ingrid Melle,