| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5844716 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 6 Pages |
Abstract
⺠IL-6 was higher in MDD-M patients compared to healthy controls. ⺠TNF-α was lower in MDD-M and MDD-A patients compared to healthy controls. ⺠Confounding factors (sex, age, BMI and smoking) did not influence cytokine levels. ⺠Clinical parameters were related to cytokine levels only in atypical depression. ⺠Duration of antidepressant treatment correlated to IL-6 in both MDD-M and MDD-A.
Keywords
TCAEKGIL-2HDRSIL-1βMDDDSMIL-6SNRIINF-γcAMPCyclic adenosine monophosphateMajor depressive disorderAtypical depressionmelancholic depressionElectroencephalogramelectrocardiograminterferon-gammainterleukin-6interleukin-1betaInterleukin-2ELISAEnzyme-linked immunosorbent assaytumour necrosis factor-αtumor necrosis factor- alphatricyclic antidepressantsAntidepressant treatmentDiagnostic and Statistical ManualCytokinesbody mass indexBMIHamilton Rating Scale for Depressionselective serotonin reuptake inhibitorsserotonin–norepinephrine reuptake inhibitorsSSRIEEG
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Authors
Bojana Dunjic-Kostic, Maja Ivkovic, Nevena V. Radonjic, Natasa D. Petronijevic, Maja Pantovic, Aleksandar Damjanovic, Sanja Totic Poznanovic, Aleksandar Jovanovic, Tanja Nikolic, Miroslava Jasovic-Gasic,