Comparison of panic disorder with and without comorbid major depression by using brain structural magnetic resonance imaging

Article ID	Journal	Published Year	Pages	File Type
5844741	Progress in Neuro-Psychopharmacology and Biological Psychiatry	2013	9 Pages	PDF

Abstract

âº Brain structural differences of panic disorder with and without comorbid depression. âº GM volume of a cluster including the left cingulate gyrus was significantly different. âº Clinical severity was positively correlated with GM volumes in PD+D group. âº FA value was significantly higher across almost all the WM tracts in PD+D group.

Keywords

ACC AC–PC anterior commissure–posterior commissure TFCE PDSS SCID-I OCD BDI FOV FWE EPI ICV VBM DTI TBSS SPM PCC ANCOVA tract-based spatial statistics Posttraumatic stress disorder PTSD Panic disorder Obsessive–compulsive disorder threshold-free cluster enhancement Comorbid depression MRI selective serotonin re-uptake inhibitor analysis of covariance echo planar imaging Magnetic resonance imaging intracranial volume SENSE family-wise error Asset Posterior cingulate gyrus sensitivity encoding echo time Repetition time posterior cingulate cortex anterior cingulate cortex Gray matter white matter Cerebrospinal fluid CSF Brodmann area SSRI Voxel based morphometry Field of view fractional anisotropy Statistical Parametric Mapping BDI, Beck Depression Inventory