Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5844802 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 8 Pages |
Abstract
The VEGFA gene polymorphism may serve as a prognostic factor for rDD development. Our study showed higher levels of both VEGFA mRNA in the peripheral blood cells and serum VEGF in patients diagnosed with rDD than in healthy controls. The obtained results suggest VEGF and the gene encoding the molecule play a role in the etiology of the disease and should be further investigated.
Keywords
iNOSM2BRPL13ARDDCIDIHDRSTMBGADPHqRT-PCRVEGFACOX-2MPORecurrent depressive disorderstandard deviationstetramethylbenzidineELISAPeripheral bloodPCR-RFLPWorld Health Organizationinducible nitric oxide synthaseLinkage disequilibriumActbconfidence intervalVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Composite International Diagnostic InterviewHamilton Depression Rating ScalemyeloperoxidaseHaplotypesquantitative real-time polymerase chain reactionWHO
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Authors
Piotr GaÅecki, Elżbieta GaÅecka, Michael Maes, Agata Orzechowska, Dominika Berent, Monika Talarowska, Kinga BobiÅska, Andrzej LewiÅski, MaÅgorzata BieÅkiewicz, Janusz Szemraj,