Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5844873 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2012 | 8 Pages |
Abstract
⺠Uliginosin B is a dimeric phloroglucinol from Brazilian Hypericum species. ⺠Uliginosin B induced antinociceptive and ataxic effects in mice. ⺠Activation of opioid, D1 and D2 receptors underlies uliginosin B effects in vivo. ⺠Uliginosin B did not alter [35S]-GTPγS binding to thalamus and striatum membranes. ⺠Uliginosin B did not alter [3H]-naloxone, [3H]-SCH 23390 and [3H]-sulpiride binding.
Keywords
GTPγSp.o.NMDAi.p.NALN-methyl-d-aspartic acidDTTMORSCH 23390SCH-23390TRPC6CIOMSDAMGOPer osSCHgamma-aminobutyric acidrepeated measuresSULPanalysis of varianceANOVAGDPstandard error of the meandithiothreitolcarbon nuclear magnetic resonanceSulpirideSEMIntraperitoneal routemorphineNaloxoneHaloperidolproton nuclear magnetic resonanceHalCodCodeinehigh performance liquid chromatographyHPLCGABAguanosine diphosphate
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Authors
Eveline Dischkaln Stolz, Alice Fialho Viana, Diego Rafael Hasse, Gilsane Lino von Poser, Jean-Claude do Rego, Stela M.K. Rates,