| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5845064 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2012 | 10 Pages |
Abstract
⺠Acetaminophen deacetylation metabolites include para-aminophenol and AM404. ⺠These may increase anandamide in the frontal cortex of socially deficient mice. ⺠Acetaminophen administration enhances mouse social and marble burying behaviors. ⺠In socially-impaired mice cortical CB1 receptor function, not density, is increased. ⺠Mouse sociability in 3-chamber tests is not altered by CB1 receptor deficiency.
Keywords
oleoylethanolamideTRISACMAM404TRPV1FAAH2-arachidonyl glycerol2-AGAEAGTP8-OH-DPAT8-hydroxy-2-(di-n-propylamino)tetralinDMSOOEAWIN 55,212-2anandamideAutoradiographyAcetaminophenFatty acid amide hydrolaseanalysis of varianceANOVAtris(hydroxymethyl) aminomethaneSocial interactionGDPmarble buryingdimethyl-sulfoxidepolymerase chain reactionPCRParacetamolWINCannabinoidhigh performance liquid chromatographyHPLCGuanosine triphosphateguanosine diphosphateCB1 receptors
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Authors
Georgianna G. Gould, Alexandre Seillier, Gabriela Weiss, Andrea Giuffrida, Teresa F. Burke, Julie G. Hensler, Crystal Rock, Amanda Tristan, Lance R. McMahon, Alexander Salazar, Jason C. O'Connor, Neera Satsangi, Rajiv K. Satsangi, Ting-Ting Gu,