| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5845079 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2012 | 11 Pages |
Abstract
⺠RS 67333, a putative antidepressant, increased the hypothalamic GR. ⺠The chronic defeat stress increased hypothalamic GR in mice with passive coping. ⺠The drug had no effect in other physiological variables. ⺠The drug showed a potential antidepressant effect in FST, decreasing immobility.
Keywords
RS 673335-hydroxytryptamine 1A5-HT1ASSRIs5-HT4FSTdeoxyribonucleaseRT-PCRGAPDHmRNAIL-6cDNADNADNAseForced swimming testdeoxyribonucleic acidcomplementary deoxyribonucleic acidRNAribonucleic acidUltravioletinterleukin-6tumour necrosis factor alphamessenger ribonucleic acidTNF-αhypothalamic pituitary adrenal axisHPA axisselective serotonin reuptake inhibitorsreverse transcription polymerase chain reactionMineralocorticoid receptorSerotonergic receptorsglucocorticoid receptorsglucocorticoid receptor
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Authors
Eneritz Gómez-Lázaro, Larraitz Garmendia, Garikoitz Beitia, Joana Perez-Tejada, Arantza Azpiroz, Amaia Arregi,