Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5845127 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 9 Pages |
Abstract
⺠Brain and cognitive reserve (BCR) can provide neuroprotective and compensatory capacities. ⺠The neurobiology of BCR has been informed by environmental manipulations of animal models. ⺠Beneficial effects of environmental enrichment have been studied in brain disease models. ⺠Enhanced sensory, cognitive and motor activity has molecular, cellular and behavioural effects. ⺠Animal models of BCR may aid development of novel therapeutics (e.g. enviromimetics).
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Authors
Jess Nithianantharajah, Anthony J. Hannan,