| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5845143 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 6 Pages |
Abstract
âºEarly non-increase of serum BDNF and early non-improvement have comparable predictive values for final treatment failure. âºThe combined marker early sBDNF non-increase plus early HAMD non-improvement predicts final treatment failure with 100% specificity. âºIf replicated, this combined marker could be considered useful for prospective confirmatory trials in patients with MDD.
Keywords
PASWD14PPVDSM-IVMDDMajor depressive disorderpositive predictive valuenegative predictive valuestandard deviationITTBiomarkerELISAEnzyme-linked immunosorbent assaybaselineDiagnostic and Statistical Manual of Mental DisordersSerumAntidepressantBrain-derived neurotrophic factorintention-to-treatNPV یا negative predictive valueTreatment outcomeEndpoint
Related Topics
Life Sciences
Neuroscience
Biological Psychiatry
Authors
André TadiÄ, Stefanie Wagner, Konrad Friedrich Schlicht, Dirk Peetz, Liudmyla Borysenko, Nadine Dreimüller, Christoph Hiemke, Klaus Lieb,