| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5845193 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 7 Pages |
Abstract
⺠Zebrafish was submitted to an unpredictable chronic stress (UCS) protocol. ⺠UCS induced anxiety, memory impairment and HPI axis activation. ⺠7 and 14 days of stress differentially modulated behavioral responses. ⺠Zebrafish may be an adequate model to preclinical studies of stress.
Keywords
PBSUCSACTHhpiRT-PCRCCACCRFCOBEAGBTinhibitory avoidanceUnpredictable chronic stressAnxietyDepressionPhosphate buffered salineHPAadrenocorticotropic hormonehypothalamus–pituitary–adrenalreverse transcription-polymerase chain reactioncortisolcorticotrophin-releasing factorZebrafishglucocorticoid receptor
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Authors
Ãngelo L. Piato, Katiucia M. Capiotti, Angélica R. Tamborski, Jean P. Oses, Leonardo J.G. Barcellos, MaurÃcio R. Bogo, Diogo R. Lara, Monica R. Vianna, Carla D. Bonan,