| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5845201 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 11 Pages |
Abstract
⺠Ten functional dopaminergic gene polymorphisms were studied in India-Caucasoid population. ⺠Significant preferential transmission of the DRD4 7R-T haplotype was observed. ⺠Bias in transmission of MAOA 3R-T & DAT1 9R-5R haplotypes was also noticed. ⺠Interaction of polymorphisms with DBH activity and hyperactivity score was detected. ⺠Data obtained indicate a “hypodopaminergic” status in Indo-Caucasoid ADHD probands.
Keywords
Dopamine receptor 4MAOADSM IVCatechol-O-methyltransferaseDBHDRD4DATCOMTVNTRDNANeurobehavioral disorderattention deficit hyperactivity disorderdeoxyribonucleic acidDopamine transporterintelligence quotientADHDhaplotype analysisGene–environment interactionGene–gene interactionVariable number of tandem repeatsdopamine beta hydroxylasemonoamine oxidase ASingle nucleotide polymorphismSNP
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Authors
Manali Das, Aneek Das Bhowmik, Nipa Bhaduri, Kanyakumarika Sarkar, Paramita Ghosh, Swagata Sinha, Anirban Ray, Anindita Chatterjee, Kanchan Mukhopadhyay,