Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5845329 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 8 Pages |
Abstract
⺠Zolpidem is a short-acting non-benzodiazepine hypnotic acting via GABAA receptors. ⺠The neuronal substrates of zolpidem within the brain are unknown. ⺠We examined how zolpidem modulates visual system activation during BOLD fMRI. ⺠Zolpidem reduced robust activation produced by a flashing checkerboard. ⺠Effects were consistent with GABA-related reductions in the BOLD signal.
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Authors
Stephanie C. Licata, Steven B. Lowen, George H. Trksak, Robert R. MacLean, Scott E. Lukas,