| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5845394 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2012 | 5 Pages |
Abstract
⺠Genetic variants can be shared among bipolar affective disorder (BPAD), major depressive disorder (MDD) and schizophrenia (SCZ). ⺠Five SNPs of ErbB4 were selected based on previous positive reports and LD information of the HapMap CHB + JPT population. ⺠These SNPs were genotyped in 1140 BPAD, 1140 SCZ, 1139 MDD patients and 1140 normal controls among Han Chinese population. ⺠Two SNPs (rs707284 and rs839523) showed significance in the BPAD patients but this was eliminated after permutation.
Keywords
SCID-IHan Chinese in Beijing, ChinaStructured Clinical Interview for DSM-IV Axis I DisordersYRIJapanese in Tokyo, JapanSHOXBPADJPTZNF804ASp4CHBCEUANK3CACNA1CNRG1ErbB4DSM-IVNeuregulin-1MDDSNPsSCZMajor depressive disorderBipolar affective disorderGenetic associationSchizophreniaLinkage disequilibriumGenome-wide association studiesCase–control studyGWASSingle nucleotide polymorphismsYoruba in Ibadan, Nigeria
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Authors
Peng Chen, Jianhua Chen, Ke Huang, Weidong Ji, Ti Wang, Tao Li, Yang Wang, Hankun Wang, Lin He, Guoyin Feng, Yongyong Shi,