| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5845677 | Pulmonary Pharmacology & Therapeutics | 2015 | 8 Pages |
Abstract
Short-term treatment with atorvastatin alone or in combination with inhaled beclometasone reduces several sputum cytokines, chemokines and growth factors concentrations unresponsive to inhaled corticosteroids alone, in smokers with asthma.
Keywords
EGFOPGCXCLICAMIP-10PAI-1MMPATSCCLTgf-αICSAQLQMDCACQsCD40LFGFMIPMCPMDALPSTNFαAsthmaOsteoprotegerinStatinsInhaled steroidsAmerican Thoracic SocietyinterferonIFNinterleukintransforming growth factor alphatumour necrosis factor-alphaGrowth related oncogeneSmokersbody mass indexBMIepidermal growth factorGranulocyte-colony stimulating factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)fibroblast growth factorG-CSFchemokine (C-C motif) ligandlipopolysaccharidechemokine (C-X-C motif) ligand soluble CD40 ligandmatrix metalloproteinasemalondialdehydePlasminogen activator inhibitor-1intercellular adhesion moleculeAsthma Control QuestionnaireAsthma Quality of Life Questionnairemonocyte chemotactic proteinmacrophage inflammatory proteininterferon gamma-induced proteinInhaled corticosteroidMacrophage-derived chemokineGro
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Authors
Neil C. Thomson, Catherine E. Charron, Rekha Chaudhuri, Mark Spears, Kazuhiro Ito, Charles McSharry,