| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5846081 | Toxicology and Applied Pharmacology | 2014 | 7 Pages |
Abstract
In the present study, we have demonstrated that VEGF-mediated angiogenesis is significantly inhibited by α-TEA, and that this effect involves inhibition of MMP-2 level through VEGFR-2-mediated FAK and p38 signaling pathways related to invasion and migration.79
Keywords
VEGFR-2EcGSFBSFAKHUVECSMmpsAngiogenesisELISAEnzyme-linked immunosorbent assayCell invasionfetal bovine serumEndothelial cellHuman umbilical vein endothelial cellsVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Matrix metalloproteinase-2Matrix metalloproteinasesCell migrationendothelial cell growth supplementfocal adhesion kinaseVEGF receptor 2
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Authors
Cheng-Hung Chuang, Chia-Hua Liu, Ta-Jung Lu, Miao-Lin Hu,