| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5846608 | Toxicology and Applied Pharmacology | 2012 | 11 Pages |
Abstract
⺠Tungsten/nickel/cobalt, tungsten/nickel/iron, and pure tungsten were studied. ⺠Male Fischer rats implanted with pellets in gastrocnemius muscle of each hind leg. ⺠Aggressive rhabdomyosarcomas developed from tungsten/nickel/cobalt pellets only. ⺠Microarray gene expression analysis was carried out on selected tumors. ⺠Pellet degradation, urinary metal concentration, and sarcoma were correlated.
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Authors
B.E. Schuster, L.E. Roszell, L.E. Murr, D.A. Ramirez, J.D. Demaree, B.R. Klotz, A.B. Rosencrance, W.E. Dennis, W. Bao, E.J. Perkins, J.F. Dillman, D.I. Bannon,