| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5846706 | Toxicology and Applied Pharmacology | 2012 | 7 Pages |
Abstract
⺠Cadmium is toxic to the kidney but the susceptibility differs between individuals. ⺠The toxic effect of cadmium is scavenged by metallothioneins. ⺠A common variant of metallothionein 1A was genotyped in 512 cadmium exposed humans. ⺠Variant carriers of this polymorphism showed more kidney damage from cadmium. ⺠The frequency of these variants needs to be taken into account in risk assessment.
Keywords
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Authors
Lijian Lei, Xiuli Chang, Gerda Rentschler, Liting Tian, Guoying Zhu, Xiao Chen, Taiyi Jin, Karin Broberg,