Article ID Journal Published Year Pages File Type
5846737 Toxicology and Applied Pharmacology 2012 8 Pages PDF
Abstract
► DADS attenuates production of NO and PGE2 in LPS-activated BV2 microglia. ► DADS downregulates levels of iNOS and COX-2. ► DADS inhibits production and expression of inflammatory cytokines and chemokine. ► DADS exhibits these effects by suppression of NF-κB, PI3K/Akt and MAPKs pathways.
Keywords
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Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Preview
Inhibitory effects of diallyl disulfide on the production of inflammatory mediators and cytokines in lipopolysaccharide-activated BV2 microglia
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