| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5846779 | Toxicology and Applied Pharmacology | 2012 | 9 Pages |
Abstract
⺠Human immortal (HaCaT) and primary (NFK) keratinocytes were exposed to PCB153. ⺠PCB153 significantly reduced telomerase activity and telomere length in HaCaT. ⺠No effect on telomere length and telomerase activity was found in NFK. ⺠Increased intracellular superoxide levels and reduced cell growth was seen in both. ⺠PCB153 may damage telomerase expressing cells like stem cells.
Keywords
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Authors
P.K. Senthilkumar, L.W. Robertson, G. Ludewig,