| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5846804 | Toxicology and Applied Pharmacology | 2012 | 8 Pages |
Abstract
⺠YC-1 potentiated PGE1-induced iNOS expression in alveolar macrophages. ⺠The combination of YC-1 and PGE1 increased CREB but not NFκB activation. ⺠The combined effects were reversed by H89. ⺠The combination of rolipram and PGE1 triggered NO production and iNOS expression. ⺠Effect of YC-1 occurred through inhibition of cAMP-specific PDE.
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Authors
Tsong-Long Hwang, Ming-Chi Tang, Liang-Mou Kuo, Wen-De Chang, Pei-Jen Chung, Ya-Wen Chang, Yao-Ching Fang,