Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5846820 | Toxicology and Applied Pharmacology | 2011 | 8 Pages |
Abstract
⺠We newly synthesized 1,3-selenazolidin-4-ones to study their possible applications. ⺠Among new compounds, compound b showed the strongest SOSA. ⺠Compound b suppressed serum deprivation-induced apoptosis in PC12 cells. ⺠Compound b suppressed apoptosis by promoting the activation of MAP kinase.
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Authors
Atsuyoshi Nishina, Hirokazu Kimura, Kunihisa Kozawa, Geoffroy Sommen, Takao Nakamura, Heinz Heimgartner, Mamoru Koketsu, Shoei Furukawa,