| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5846824 | Toxicology and Applied Pharmacology | 2011 | 7 Pages |
Abstract
⺠OPN-CD44 pathway plays a critical role in the development of atherosclerosis. ⺠We examine lesion area, OPN and CD44 changes after kaempferol treatment. ⺠Kaempferol treatment decreased atherosclerotic lesion area in ApoEâ/â mice. ⺠Kaempferol treatment decreased aortic OPN and CD44 expressions in ApoEâ/â mice. ⺠Kaempferol regulates OPN-CD44 pathway to inhibit the atherogenesis.
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Authors
Hong-Bo Xiao, Xiang-Yang Lu, Zhi-Liang Sun, Heng-Bo Zhang,