| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5846850 | Toxicology and Applied Pharmacology | 2011 | 8 Pages |
Abstract
⺠CDDO-Me treatment increased intracellular GSH in human keratinocytes. ⺠CDDO-Me increased cell viability following exposure to the half-mustard, CEES. ⺠The cytoprotective effect of CDDO-Me was likely due to scavenging with endogenous GSH.
Keywords
DMEMCDNBGCLCNDAGCLMGSTGSHCEEsDTTSSADTP1-chloro-2,4-dinitrobenzene2-Chloroethyl ethyl sulfideCDDO-ImCDDO-MeDMSODulbecco's modified Eagle's mediumEDTAEthylenediaminetetraacetic acidSulfosalicylic aciddithiothreitolDimethyl sulfoxideCytotoxicitySulfur mustardNEMKeratinocytesglutamate cysteine ligase modifier subunitGlutamate cysteine ligase catalytic subunitGlutathioneglutathione S-transferase
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Authors
Erika L. Abel, Jennifer D. Bubel, Melissa S. Simper, Leslie Powell, S. Alex McClellan, Michael Andreeff, Michael C. MacLeod, John DiGiovanni,