Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5846912 | Toxicology and Applied Pharmacology | 2011 | 9 Pages |
Abstract
⺠Ni suppressed ÎNp63 expression in HaCat cells. ⺠Ni activated NF-κB, decreased expressions of IRF3 and IRF7, IKKε, and Sp100. ⺠Over-expression of IRF3 increased ÎNp63 expression suppressed by Ni. ⺠Ni activated p21, and its activation was offset by over-expression of ÎNp63. ⺠Elevated p63 expression counteracted the ability of nickel to restrict cell growth.
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Authors
Zhuo Zhang, Wenqi Li, Senping Cheng, Hua Yao, Fan Zhang, Qingshan Chang, Zunji Ke, Xin Wang, Young-Ok Son, Jia Luo, Xianglin Shi,