Telmisartan attenuates hyperglycemia-exacerbated VCAM-1 expression and monocytes adhesion in TNFÎ±-stimulated endothelial cells by inhibiting IKKÎ² expression

Article ID	Journal	Published Year	Pages	File Type
5847223	Vascular Pharmacology	2016	61 Pages	PDF

Keywords

ARB BAEC TNFα receptor TNFR VCAM-1 GSK3β ELAM-1 IL-1β IKKβ PPARγ HUVEC ICAM-1 NF-κB TNFα IκB kinase β Angiotensin II type 1 receptor blocker Vascular inflammation Interleukin-1β cardiovascular disease Telmisartan tumor necrosis factor α Diabetes mellitus CVD Human umbilical vein endothelial cells Bovine aortic endothelial cells nuclear factor κB endothelial-leukocyte adhesion molecule-1 intercellular adhesion molecule-1 vascular cell adhesion molecule-1 wild type Hyperglycemia Glycogen synthase kinase 3β peroxisome proliferator-activated receptor γ

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Telmisartan attenuates hyperglycemia-exacerbated VCAM-1 expression and monocytes adhesion in TNFÎ±-stimulated endothelial cells by inhibiting IKKÎ² expression

Authors

Kee-Ho Song, Jung-Hyun Park, Inho Jo, Joong-Yeol Park, Jungwon Seo, Soon Ae Kim, Du-Hyong Cho,