| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 584738 | Journal of Hazardous Materials | 2007 | 4 Pages |
Abstract
IC50 values of vankomycine, sulfanylamide, sulfanylacetamide, nidazole, ciprofloxacin, amoxicillin and KMnO4 were 1.88, 0.037, 0.032, 1.178, 2.26, 643.5 and 0.0002 mM, and the Ki constants 1.18 ± 0.148, 0.119 ± 0.021, 0.075 ± 0.015, 1.15 ± 0.21, 7.69 ± 0.67, 1007 ± 69, and 0.001 ± 0.00022 mM, respectively. While vankomycine and nidazole showed competitive inhibition, others displayed noncompetitive inhibition. Ki constants and IC50 values for drugs were determined by Lineweaver-Burk graphs and plotting activity percentage versus [I], respectively.
Keywords
Related Topics
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Chemical Engineering
Chemical Health and Safety
Authors
Mehmet Ciftci, Vedat Turkoglu, T. Abdulkadir Coban,