Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta

Article ID	Journal	Published Year	Pages	File Type
5847591	Vascular Pharmacology	2012	7 Pages	PDF

Keywords

COX 15-hydroperoxyeicosatetraenoic acid 15-HPETE 15-LO-1 SKCa 15-lipoxygenase-1 guanylate cyclase ODQ CYP450 SMCs LNA NOS NDGA PHE HEPES DPTA 15-Lipoxygenase 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid Vascular relaxation cyclooxygenase ACh Acetylcholine Arachidonic acid nordihydroguaiaretic acid Indomethacin Theta Smooth muscle cells Cytochrome P450 endothelium-derived hyperpolarizing factors phenylephrine lipoxygenase nitro-l-arginine Nitric oxide nitric oxide synthase indo Potassium prostaglandin high-pressure liquid chromatography HPLC

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Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta

Authors

Nitin T. Aggarwal, Kathryn M. Gauthier, William B. Campbell,