Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5848229 | Chemico-Biological Interactions | 2013 | 13 Pages |
Abstract
⺠OPG-based peptide YR-11 has dual suppressive activity on bone loss and inflammation. ⺠YR-11 reduced systemic cytokine levels in AIA rats via inhibition of NF-κB activation. ⺠In vitro and in vivo evidences are presented. ⺠The novel peptide could be useful as a new therapeutic for rheumatoid arthritis.
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Authors
V.G.M. Naidu, Kuppan Rajendran Dinesh Babu, Maung Maung Thwin, R.L. Satish, Prem V. Kumar, P. Gopalakrishnakone,