| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5848232 | Chemico-Biological Interactions | 2013 | 6 Pages |
Abstract
- Five aromatic or polycyclic aromatic glutathione conjugates were synthesized.
- Enzyme kinetic studies were performed for each conjugate as a γ-glutamyltransferase (GGT) donor substrate.
- All conjugates tested were substrates for GGT, with a possible trend towards higher Km values for bulkier substrates.
- These results clarify the ability of GGT to act in the biotransformation of aromatic compounds.
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Authors
Anita A. Agblor, P. David Josephy,