| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5848239 | Chemico-Biological Interactions | 2013 | 8 Pages |
Abstract
⺠Baicalin inhibited DXM O- and N-demethylase activity in rats liver microsomes. ⺠Baicalin decreased the CL of DXM, with a concomitant increase in the AUC in rats. ⺠Baicalin inhibited DXM metabolism in concentration-dependent manner in rats. ⺠Multiple doses of baicalin decreased DXM N-demethylase activity in an ex vivo study.
Keywords
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Xin Tian, Zhen-Yu Cheng, Jing He, Lin-Jing Jia, Hai-Ling Qiao,