Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5848281 | Chemico-Biological Interactions | 2013 | 4 Pages |
Abstract
⺠Library of 30 uncharged oximes was tested as reactivators tabun-inhibited ChE. ⺠Imidazole-containing oximes preferred tabun-hAChE conjugate. ⺠Hydroxyimino acetamido amine derivatives preferred tabun-hBChE conjugate. ⺠Three-times faster mutant Y337A reactivation with nontriazole oximes than with 2PAM.
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Authors
Zrinka Kovarik, Nikolina MaÄek, Rakesh K. Sit, Zoran RadiÄ, Valery V. Fokin, K. Barry Sharpless, Palmer Taylor,