| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5848339 | Chemico-Biological Interactions | 2013 | 6 Pages |
Abstract
⺠Organophosphorus nerve agents neutralization is an important task. ⺠Antibodies with catalytic activity (abzymes) may be effectively used for this purpose. ⺠Transition state analogs approach is widely used for abzyme generation. ⺠Anti-idiotypic antibodies are internal image of phosphorous-metabolizing enzymes. ⺠Reactibodies are novel class of abzymes with pre-determinate mechanism of catalysis.
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Authors
Ivan Smirnov, Alexey Jr., Alain Friboulet, Patrick Masson, Alexander Gabibov, Pierre-Yves Renard,