| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5848359 | Chemico-Biological Interactions | 2013 | 7 Pages |
Abstract
⺠A brief overview of neuropathy target esterase (NTE) is presented. ⺠Toxicological data support NTE aging as the trigger for OP neuropathy. ⺠Conditional NTE knockouts and mutations result in neurodegeneration. ⺠NTE is a phospholipase: PNPLA6, nearly identical to insulin-regulated PNPLA7. ⺠Future research: is NTE regulated by insulin and involved in diabetic neuropathy?
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Authors
Rudy J. Richardson, Nichole D. Hein, Sanjeeva J. Wijeyesakere, John K. Fink, Galina F. Makhaeva,