Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5848437 | Chemico-Biological Interactions | 2012 | 10 Pages |
Abstract
⺠We compared the effects of the 4-methylesculetin with sulphasalazine and prednisolone. ⺠4-Methylesculetin produced better anti-inflammatory effects than sulphasalazine. ⺠4-Methylesculetin produced similar anti-inflammatory effects than prednisolone. ⺠The action is related to antioxidant effect and inhibition of cytokine production. ⺠4-Methylesculetin is a potential compound for treatment of intestinal inflammation.
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Authors
Aline Witaicenis, Ana C. Luchini, Clélia A. Hiruma-Lima, Sérgio L. Felisbino, Natividad Garrido-Mesa, Pilar Utrilla, Julio Gálvez, Luiz C. Di Stasi,