| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5848444 | Chemico-Biological Interactions | 2012 | 8 Pages |
Abstract
⺠We examined in vitro bioactivation of bazedoxifene and N-dealkylated fragment of bazedoxifene in HLM and with P450 isozymes. ⺠Bazedoxifene was not bioactivated under either conditions. ⺠An improved safety profile of bazedoxifene to available SERMs was discussed.
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Authors
Tina Trdan LuÅ¡in, Tihomir TomaÅ¡iÄ, Jurij Trontelj, AleÅ¡ Mrhar, Lucija Peterlin-MaÅ¡iÄ,