Article ID Journal Published Year Pages File Type
5848447 Chemico-Biological Interactions 2012 9 Pages PDF
Abstract
► Ethanol consumption induces gastric ulcers and low levels of zinc. ► Zn(II)-curcumin was a metallocomplexes of curcumin, stimulated cell proliferation and blocked the ulcer lesions. ► Zn(II)-curcumin revealed more patent antioxidant than curcumin. ► Zn(II)-curcumin processes the anti-inflammatory effect by downregulation of TNF-α and IL-6. ► Zn(II)-curcumin enhanced mucosal barrier defenses by adjusting the proinflammatory cytokine-mediated oxidative damage.
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