Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5848455 | Chemico-Biological Interactions | 2011 | 12 Pages |
Abstract
⺠Mangiferin attenuates methylmercury induced cytotoxicity in IMR-32 cells. ⺠Pretreatment with mangiferin reduced methylmercury induced oxidative stress. ⺠Mangiferin aided in restoration of ÎΨm along with cytosolic Ca2+ homeostasis. ⺠Inhibition of apoptosis by downregulating bax, caspase-3 and cytochrome c release. ⺠Cytoprotection by mangiferin do not entail role of microtubule and metallothionein.
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Authors
Shubhankar Das, B. Nageshwar Rao, B.S. Satish Rao,