Article ID Journal Published Year Pages File Type
5848455 Chemico-Biological Interactions 2011 12 Pages PDF
Abstract
► Mangiferin attenuates methylmercury induced cytotoxicity in IMR-32 cells. ► Pretreatment with mangiferin reduced methylmercury induced oxidative stress. ► Mangiferin aided in restoration of ΔΨm along with cytosolic Ca2+ homeostasis. ► Inhibition of apoptosis by downregulating bax, caspase-3 and cytochrome c release. ► Cytoprotection by mangiferin do not entail role of microtubule and metallothionein.
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