Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5848513 | Chemico-Biological Interactions | 2012 | 8 Pages |
Abstract
⺠S1 was about 100 times more efficient than O-trensox to decrease cell proliferation. ⺠The antiproliferative effect of S1 appeared at concentrations as low as 0.1 μM. ⺠The stoichiometry of S1 for iron seemed to be in the range S1/Fe3+ = 1. ⺠S1 affinity for iron was higher than that of O-trensox. ⺠S1 may constitute a promising starting point to improve cancer treatment.
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Authors
Gérard Lescoat, Stéphane Léonce, Alain Pierré, Lucie Gouffier, François Gaboriau,